CAR T cell cancer immunotherapy, illustration
by Juan Gaertner/science Photo Library
Title
CAR T cell cancer immunotherapy, illustration
Artist
Juan Gaertner/science Photo Library
Medium
Drawing - Illustration
Description
CAR T cell cancer immunotherapy. Illustration of the membrane of a cell involved in CAR (chimeric antigen receptor) T cell immunotherapy, a process that is being developed to treat cancer. In this process, T cells (part of the immune system) are treated with a virus in a form of genetic engineering, resulting in them producing chimeric antigen receptor (CAR) proteins. These proteins will be specific to the patient's cancer. Here, these engineered receptors (light blue, one at upper right) bind specifically to CD19-antigen molecules (purple), in this case on a leukaemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme (yellow) molecules. The perforins build channels for the granzymes which enter the leukaemia cell and trigger the apoptosis (cell death) of the cancer cell.
Image provided by Getty Images.
Uploaded
December 28th, 2019
Statistics
Viewed 64 Times - Last Visitor from New York, NY on 04/20/2024 at 10:25 PM
Embed
Share
Sales Sheet
Tags
Image ID
1128676531
Comments
There are no comments for CAR T cell cancer immunotherapy, illustration. Click here to post the first comment.